Ceftriaxone Sodium

Ceftriaxone sodium waa β-lactamase- adkaysta cephalosporin oo leh serum noloshii badhkeed oo aad u dheer. Laba arrimood ayaa gacan ka geysta muddada dheer ee ficilka ofceftriaxone: borotiinka sare ee ku xiran balaasmaha iyo soo saarista gaabis ah. Ceftriaxone waxaa laga soo saaraa bile iyo kaadida labadaba. Soosaarkeeda kaadidu ma saamayso byprobenecid. In kasta oo qaybinteedu hoosayso marka la barbardhigo, waxay gaartaa dareeraha maskaxda ee maskaxda oo waxtar u leh qoorgooyaha. Farmashiyaha aan tooska ahayn ayaa la arkay.
Ceftriaxone waxaa ku jira nidaam heterocyclic heterocyclic aad u sarreeya oo ku jira kooxda 3-thiomethyl. Nidaamkan giraanta ah ee dioxotriazine ee aan caadiga ahayn ayaa la rumeysan yahay inuu bixiyo hantida farmasiga ee gaarka ah ee wakiilkan. Ceftriaxone waxa lala xidhiidhiyay sonografi ahaan lagu ogaaday “sludge,” ama pseudolithiasis, ee ku jira xameetida iyo duct bile caadiga ah. Calaamadaha cholecystitis-ka waxay ku dhici karaan bukaanada u nugul, gaar ahaan kuwa qaata daawaynta ceftriaxone ee dheer ama qiyaasta sare. Dambiilaha waxaa loo aqoonsaday inuu yahay calcium chelate.
Ceftriaxone waxay soo bandhigtaa firfircoonida bakteeriyada ballaaran ee ballaaran ee lidka ku ah Gram-positive iyo Gram-negative. Aad ayey ugu adkeysneysaa inta badan koromosoomyada iyo balaassamida β-lactamase. Waxqabadka ceftriaxone ee ka dhanka ah Enterobacter, Citrobacter, Serratia, indole-positiveProteus, iyo Pseudomonas spp. gaar ahaan waa mid cajiib ah. Waxa kale oo ay wax ku ool u tahay daawaynta jabtada u adkaysata ampicillin iyo caabuqyada hargabka H. laakiin guud ahaan way ka firfircoon tahay cefotaxime ka hortagga bakteeriyada Gram-positive iyo B.fragilis.