Sharaxaad Gaaban:
Lambarka CAS: 58-55-9
Qaaciddada molecular: C7H8N4O2
Miisaanka molecular:180.16
Qaab dhismeedka kiimikada:
| Macluumaadka aasaasiga ah | |
| Magaca alaabta | Theophylline Anhydrous |
| CAS Maya. | 58-55-9 |
| Muuqashada | caddaan ilaa iftiin jaale ah powder |
| Xasilooni | Deggan Aan ku habboonayn walxaha oksaydhaynta ee xooggan. |
| Biyuhu milmayn | 8.3 g/L (20ºC) |
| Kaydinta | 2-8°C |
| Nolosha shelf | 2 Ydhegaha |
| Xidhmada | 25kg/Durbaan |
Sharaxaada Alaabta
Theophylline waa methylxanthine ka shaqeeya sidii bronchodilator daciif ah. Waxay faa'iido u leedahay daaweynta dabadheeraad ah mana aha mid waxtar u leh sii xumeynta degdega ah.
Theophylline waa methylxanthine alkaloid kaas oo ah xakameynta tartanka fosfodiesterase (PDE; Ki = 100 μM). Sidoo kale waa iska soo horjeeda aan la dooran ee adenosine A reseptors (Ki = 14 μM ee A1 iyo A2). Theophylline waxa ay keentaa nasinta muruqa sambabada ah ee bronkiole oo ay hore heshiis ula gashay acetylcholine (EC40 = 117 μM; EC80 = 208 μM). Daawooyinka ay ku jiraan theophylline ayaa loo isticmaalay daawaynta neefta iyo cudurada sambabada xanniba ee joogtada ah (COPD).
Codsiga
1.Daawaynta neefta: Theophylline waxay kaa caawin kartaa yaraynta calaamadaha neefta iyadoo kala furfuraysa marinnada bronki iyo kordhinta nasashada muruqa.
2.Daaweynta cudurada wadnaha: Theophylline waxay u adeegi kartaa vasodilator, caawinta hagaajinta calaamadaha cudurka wadnaha.
3.Kicinta habdhiska dhexe ee neerfayaasha: Theophylline waxa loo isticmaalaa dawooyinka qaar kiciya habdhiska dhexe ee neerfayaasha, kor u qaadida feejignaanta iyo dareenka.
4.Nidaaminta dheef-shiid kiimikaadka dufanka: Theophylline waxay kor u qaadi kartaa burburka baruurta waxaana la rumeysan yahay inay caawineyso xakameynta miisaanka iyo dhimista miisaanka.
