Sharaxaad Gaaban:
Lambarka CAS: 137-88-2
Qaaciddada molecular: C14H20Cl2N4
Miisaanka molecular: 315.24
Qaab dhismeedka kiimikada:
| Macluumaadka aasaasiga ah | |
| Magaca alaabta | Oxytetracycline hydrochloride |
| Darajo | Fasalka Quudinta/Fasalka Farmashiyaha |
| Muuqashada | Budada crystalline jaalaha ah |
| Qiimayn | 99% |
| Nolosha shelf | 2 Sano |
| Baakad | 25kg/durbaan |
| Xaalad | Ku hay meel qabow, qalalan, mugdi ah weel si adag u xiran ama dhululubo. |
Hordhaca Oxytetracycline hydrochloride
Oxytetracycline hydrochloride waa jaale cirro leh, qadhaadh, crystalline. Saldhigga amphoteric waa in yar oo biyo ah oo wax yar ku milma khamriga. Waa ur aan ur lahayn oo xasiloon hawadu laakiin way madoobaataa marka ay soo gaadho iftiinka qoraxda. Aad bay ugu milmi kartaa biyaha, 1 g oo ku milma 2 mL, iyo in ka badan oo ku milma khamriga ka badan saldhigga bilaashka ah. Labada xeryoodba si degdeg ah ayey u firfircoon yihiin alkali hydroxides iyo xalalka acid ee ka hooseeya pH 2. Labada nooc ee oxytetracycline ayaa si degdeg ah u nuugaya oo si siman uga soo baxa habka dheef-shiidka, sidaas darteed faa'iidada kaliya ee dhabta ah ee saldhigga bilaashka ah ayaa bixiya cusbada hydrochloride waa in ay ka yar tahay qadhaadh. . Oxytetracycline hydrochloride ayaa sidoo kale loo isticmaalaa maamulida parenteraladministration (xididka iyo muruqyada gudaha).
Codsiga Oxytetracycline hydrochloride
Oxytetracycline hydrochloride waa milix laga soo diyaariyey oxytetracycline iyada oo ka faa'iidaysanaysa kooxda aasaasiga ah ee dimethyl amino taasoo protonates si diyaar ah si ay u sameeyaan milixda xalalka hydrochloric acid. Hydrochloride-ka ayaa ah qaabaynta la door biday ee codsiyada dawooyinka. Sida dhammaan tetracyclines, oxytetracycline waxay muujinaysaa firfircoonida bakteeriyada iyo antiprotozoan ballaaran waxayna u dhaqmeysaa iyadoo lagu xirayo cutubyada 30S iyo 50S ee ribosomal, xannibaya isku-dhafka borotiinka.
Oxytetracycline waa antibiyootig loo tilmaamay in lagu daweeyo caabuqyada ay sababaan Gram positive microorganisms sida Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, iyo Diplococcus pneumoniae. Waxaa loo isticmaalaa daraasadaha ku saabsan hidda-wadaha iska caabinta oxytetracycline (otrA). Oxytetracycline hydrochloride waxaa loo isticmaalaa in lagu barto phagosome-lysosome (PL) fusion ee unugyada P388D1 iyo u nuglaanta antibiyootiga ee Mycoplasma bovis.
