Sharaxaad Gaaban:
Lambarka CAS: 1405-10-3
Qaaciddada molecular: C23H48N6O17S
Miisaanka molecular: 712.72
Qaab dhismeedka kiimikada:
| Macluumaadka aasaasiga ah | |
| Magaca alaabta | Neomycin sulfate |
| CAS Maya. | 1405-10-3 |
| Muuqashada | Budada Jaalle Cadaan ilaa Inyar |
| Darajo | Farmaajo Fasalka |
| Biyuhu milmayn | Biyo ku milmay |
| Kaydinta | 2-8°C |
| Nolosha shelf | 2 Ydhegaha |
| Xidhmada | 25kg/Durbaan |
Sharaxaada Alaabta
Neomycin sulfate waa antibiyootiko aminoglycoside ah iyo kaalshiyam borotiinka xannibaya. Neomycin sulfate waxa kale oo ay ku xidhaa ribosomes-ka prokaryotic ee joojiya tarjumaada waxayna wax ku ool u tahay bakteeriyada garaam-positive iyo gram-negative. Neomycin sulfate waxay joojisaa PLC (Phospholipase C) iyada oo loo marayo inositol phospholipids. Waxay sidoo kale joojisaa dhaqdhaqaaqa fosfatidylcholine-PLD waxayna kicisaa abaabulka Ca2+ iyo firfircoonida PLA2 ee platelets ee aadanaha. Neomycin sulfate waxay xakameysaa DNA-da DNA-da ee DNA-da. Waxa loo isticmaalaa in lagaga hortago ama lagu daweeyo caabuqyada maqaarka ee ay keento bakteeriyada. Wax ku ool uma aha caabuqyada fangas ama fayraska.
Codsiga
Neomycin sulfate waa antibiyootig aminoglycoside ah oo ay soo saarto S. fradiae taas oo joojisa tarjumaada borotiinka iyada oo ku xidhan qaybta yar ee ribosomes prokaryotic. Waxay xannibaysaa kanaalada Ca2+ ee danab-ku-oolka ah waana ka-hortag awood leh oo ka hortagta muruqa lafaha lafaha ee sarcoplasmic reticulum Ca2+ sii-deynta. NEOMYCIN SULFATE ayaa lagu muujiyay in ay joojiso wareegga fosfolipid inositol phospholipid, phospholipase C, iyo fosfatidylcholine-phospholipase D dhaqdhaqaaqa (IC50 = 65 μM). Waxay aad waxtar ugu leedahay bakteeriyada Gram-positive iyo Gram-negative waxaana badanaa loo isticmaalaa ka hortagga wasakhowga bakteeriyada ee dhaqamada unugyada.
