Sharaxaad Gaaban:
Lambarka CAS: 70288-86-7
Qaaciddada molecular: C48H74O14
Miisaanka molecular: 875.09
Qaab dhismeedka kiimikada:
| Macluumaadka aasaasiga ah | |
| Magaca alaabta | Ivermectin |
| Darajo | Darajada Dawooyinka |
| Muuqashada | budo cad |
| Qiimayn | 99% |
| Nolosha shelf | 2 sano |
| Baakad | 25kg/ kartoon |
| Xaalad | Meel qalalan oo qabow |
Sharaxaada Ivermectin
Ivermectin waa wakiilka antiparasitic oo wax ku ool u ah daaweynta onchocerciasis, ama "indho la'aanta webiga". Maadaama ivermectin uu ka hortagayo gooryaanka qaangaarka ah inuu soo saaro microfilariae, waxay u baahan tahay in la isticmaalo hal mar ama laba jeer sannadkii.
Saamaynta Ivermectin
Ivermectin waa caddaan ama budo crystalline jaale ah waxayna ku milmi kartaa methyl alkohol, ester iyo hydrocarbon udgoon laakiin biyo ah. Ivermectin waa nooc ka mid ah dawooyinka antibiyootiga kaas oo wadista iyo dilka saamaynta ku leh nematodes, cayayaanka iyo caarada. Duritaan iyo troche oo laga sameeyo ivermectin ayaa inta badan loo isticmaalaa daawaynta nematode mindhicirka xoolaha, hypodermosis lo'da, dirqaha duqsiga, dirxiga sanka ee idaha, iyo maqaarka maqaarka idaha iyo doofaarrada. Ka sokow, ivermectin sidoo kale waxay diyaar u noqon kartaa daaweynta nematodes-ka- dulin dhirta (ascarid, lungworm) ee digaagga. Intaa waxaa dheer, waxaa sidoo kale laga dhigi karaa cayayaanka beeraha si loo dilo caarada, plutella xylostella, diirka kaabajka, macdanta caleen, phylloxera iyo nematode kuwaas oo si weyn u dulin dhirta. Tilmaamaha ugu caansan ee cayayaankan ayaa ah in ay leedahay waxyeelo yar oo ay wadi karto oo dili karto noocyo badan oo dulin ah oo gudaha iyo dibaddaba ah markiiba.
Pharmacology ee Ivermectin
Ivermectin waxay ka tirsan tahay maaddooyinka loo yaqaan 'avermectins'. Kuwani waa lactones makrocylic ah oo ay soo saarto halsano ee actinomycete, Streptomyces avermitilis. Ivermectin waa walax ballaadhan oo ka soo horjeeda nematodes iyo arthropods ee xayawaanka guriga sidaas darteed si ballaaran ayaa loogu isticmaalaa daawada xoolaha[1]. Daawada ayaa markii ugu horeysay lagu soo bandhigay nin 1981. Waxaa la muujiyay in ay waxtar u leedahay noocyo badan oo nematodes ah sida Strongyloides sp., Trichuris trichiura, Enterobius vermicularis, Ascaris lumbricoides, hookworms iyo Wuchereria bancrofti. Si kastaba ha ahaatee, wax saameyn ah kuma laha hargabka beerka iyo cestodes[2].
