Macluumaadka aasaasiga ah | |
Magaca alaabta | Cefoperezone sodium + sulbactam sodium (1: 1/2: 1) |
Dabeecad | Budada |
CAS Maya. | 62893-20-3 693878-84-7 |
Midabka | Caddaan ilaa budo khafiif ah |
Nolosha shelf | 2 Sano |
Heerka Heerka | Darajada daawada |
daahirnimo | 99% |
CAS Maya. | 62893-20-3 |
Xidhmada | 10kg/durbaan |
Sharaxaada
Sharaxaad:
Cefoperzonone sodium + sulbactam sodium (1: 1/2: 1) waa waalid-firfircoon, β-lactamase inhibitor dhawaan loo soo bandhigay sida 1: 1 badeeco isku dhafan oo leh cefoperazone. Sida clavulanic acid, wakiilka ugu horreeya ee noocaan ah ee la soo bandhigo, sulbactam waxay wanaajisaa waxtarka antibiyootiga β-lactam ee ka hortagga noocyada adkaysiga leh.
Isticmaalka:
β-lactamase inhibitor-ka-soo-baxa ah. Waxaa lagu daraa antibiyootiga β-lactam sida bakteeriyada.
Cefoperzonone sodium cusbada waa antibiyootiga cephalosporin ee ka hortagga rMrp2-dhexdhexaadin [3H] E217βG qaadashada IC50 ee 199 μM. Bartilmaameedka: Antibakteeriyada Cefoperazone waa nadiifiye, semisynthetic, antibiyootiko cephalosporin parenteral ah oo loogu talagalay maamulka xididada ama muruqyada. Ka dib markii la maamulay xididada 2 g ee Cefoperazone, heerarka serumku waxay u dhexeeyaan 202μg/mL ilaa 375 μg/mL iyadoo ku xidhan muddada maamulka daroogada. Ka dib duritaanka intramuscularly ee 2 g ee Cefoperazone, celceliska heerka serum ee ugu sarreeya waa 111 μg/mL 1.5 saacadood. 12 saacadood ka dib qaadashada, celceliska heerka serum weli waa 2 ilaa 4 μg/mL. Cefoperazone waxay 90% ku xidhan tahay borotiinnada serum.