Sharaxaad Gaaban:
Lambarka CAS: 83905-01-5
Qaaciddada molecular: C38H72N2O12
miisaanka kelli: 748.98
Qaab dhismeedka kiimikada:
| Macluumaadka aasaasiga ah | |
| Magaca alaabta | Azithromycin |
| CAS Maya. | 83905-01-5 |
| Muuqashada | budo crystalline cad |
| Darajo | Farmaajo Fasalka |
| daahirnimo | 96.0-102.0% |
| cufnaanta | 1.18±0.1 g/cm3 (La saadaaliyay) |
| qaab | nadiif ah |
| Xasilooni | Deggan Aan ku habboonayn walxaha oksaydhaynta ee xooggan |
| Xidhmada | 25kg/durbaan |
Sharaxaada Alaabta
Azithromycin waxay ahayd tii ugu horreysay ee azalides waxaana loogu talagalay inay hagaajiso xasilloonida iyo nolosha nuska noolaha ee erythromycin A, iyo sidoo kale hagaajinta dhaqdhaqaaqa ka hortagga bakteeriyada Gram negative. Azithromycin waa antibiyootik macrolide oo muddo dheer shaqaynaysa oo qaabdhismeed ahaan la xidhiidha erythromycin A (EA), oo leh nitrogen methyl-lagu beddelay booska 9a ee giraanta aglycone.
Codsiga Alaabta
Azithromycin waxay iska leedahay antibiyootiga ballaaran waana antibiyootiga jiilka labaad ee macrolides. Saamaynta ugu weyni waa caabuqyada mareenka neef-mareenka, maqaarka iyo unugyada jilicsan ee ay sababaan bakteeriyada xasaasiga ah iyo cudurrada faafa ee kalamiidiya. Waxay leedahay saameyn daweyn oo wanaagsan oo ku saabsan caabuqyada boronkiitada ba'an ee ay keento bakteeriyada hargabka, pneumococci, iyo Moraxella catarrhalis, iyo sidoo kale cudurrada sambabada xannibaadda ee joogtada ah ee sambabada.Marka lagu daro xaaladaha kor ku xusan, azithromycin sidoo kale waa daawo caadi ahaan loo isticmaalo ka hortagga xumadda laabotooyinka. Haddii si adag loo isticmaalo hagida dhakhtarka, waxa kale oo lagu dari karaa diyaargarowga dexamethasone acetate si loo xakameeyo cudurka. Waxa kale oo loo isticmaali karaa infekshannada fudud ee xubnaha taranka ee uu keeno Neisseria gonorrhoeae ee aan dawooyinka badan u adkaysan karin, iyo sidoo kale cudurrada ay ka midka yihiin chancre ee uu keeno Haemophilus duke.Si kastaba ha noqotee, waa in la ogaadaa in haddii mid ka mid ah uu xasaasiyad ku leeyahay azithromycin, erythromycin, iyo daawooyinka kale ee macrolide, isticmaalkooda waa in la mamnuucaa. Shakhsiyaadka leh taariikhda cagaarshow cholestatic iyo cillad beerka waa inaysan isticmaalin dawadan. Haweenka uurka leh iyo naagaha nuujinaya waa in ay si adag u raacaan talada caafimaadka oo ay isticmaalaan daawada si taxadar leh si ay uga fogaadaan in ay saameeyaan uurjiifka ama ilmaha.
