Sharaxaad Gaaban:
Lambarka CAS: 7177-48-2
Qaaciddada molecular: C16H25N3O7S
Miisaanka molecular: 403.45
Qaab dhismeedka kiimikada:
| Macluumaadka aasaasiga ah | |
| Magaca alaabta | Ampicillin |
| Darajo | Darajada Dawooyinka |
| Muuqashada | Caddaan ama ku dhawaad cad, budada crystalline |
| Qiimayn | |
| Nolosha shelf | 2 Sano |
| Baakad | 25kg/durbaan |
| Xaalad | lagu kaydiyaa meel qabow oo qallalan |
Sharaxaada
Sida kooxda penicillin ee beta-lactam antibiyootiga, Ampicillin waa penicillin-ka ballaadhan ee ugu horreeya, kaas oo leh firfircooni firfircoon oo ka dhan ah bakteeriyada Gram-positive iyo Gram-negative aerobic iyo anaerobic bakteeriyada, oo caadi ahaan loo isticmaalo ka hortagga iyo daaweynta caabuqyada bakteeriyada ee habka neefsashada, kaadi mareenka. Mareenka, dhegta dhexe, sanka, caloosha iyo mindhicirrada, kaadiheysta, iyo kelyaha, iwm oo ay keento bakteeriyada u nugul. Waxa kale oo loo isticmaalaa in lagu daweeyo jabtada aan dhibsanayn, qoorgooyaha, endocarditis salmonellosis, iyo infekshannada kale ee halista ah iyada oo laga maareeyo afka, cirbadeynta muruqyada ama faleebo xididka. Sida antibiyootiga oo dhan, waxtar uma laha daaweynta caabuqyada fayraska.
Ampicillin waxay u shaqeysaa iyadoo disha bakteeriyada ama ka hortagta korriimadooda. Ka dib marka la dhex galo bakteeriyada Gram-positive iyo Gram-negative, waxay u shaqeysaa sidii horjooge aan la bedeli karin ee transpeptidase enzyme ay u baahan tahay bakteeriyadu si ay u sameeyaan derbiga unugga, taas oo keenta in la joojiyo isku-darka gidaarka unugga oo ugu dambeyntii keena lysis unug.
Dhaqdhaqaaqa ka hortagga jeermiska
Ampicillin aad ayuu uga yar yahay benzylpenicillin marka loo eego bakteeriyada Gram-positive-ka ugu badan laakiin waxa uu aad uga firfircoon yahay E. saxarada. MRSA iyo noocyada Str. pneumoniae ay hoos u dhigtay u nuglaanshaha benzylpenicillin ayaa adkaysi u leh. Inta badan kooxda D streptococci, anaerobic Gram-positive cocci iyo bacilli, oo ay ku jiraan L. monocytogenes, Actinomyces spp. iyo Arachnia spp., waa u nugul yihiin. Mycobacteria iyo nocardia way iska caabiyaan.
Ampicillin waxay leedahay hawl la mid ah tan benzylpenicillin ee ka dhanka ah N. jabtada, N. meningitidis iyo Mor. catarrhalis. Waxay 2-8 jeer ka firfircoon tahay benzylpenicillin ka hortagga hargabka H. iyo Enterobacteriaceae badan, laakiin noocyada soo saara β-lactamase ayaa iska caabiya. Pseudomonas spp. waa adkaysi, laakiin Bordetella, Brucella, Legionella iyo Campylobacter spp. inta badan waa u nugul yihiin. Qaar ka mid ah anaerobes Gram-negative sida Prevotella melaninogenica iyo Fusobacterium spp. waa u nuglaadaan, laakiin B. Jilicsanaanta waa adkaysi, sida mycoplasmas iyo rickettsiae.
Dhaqdhaqaaq ka dhan ah fasalka molecular A β-lactamase-soo saara noocyada staphylococci, gonococci, H. influenzae, Mor. catarrhalis, qaar ka mid ah Enterobacteriaceae iyo B. fragilis waxaa xoojisay joogitaanka β-lactamase inhibitors, gaar ahaan clavulanic acid.
Dhaqdhaqaaqeeda bakteeriyada waxay u egtahay tii benzylpenicillin. Isku-dhafka bakteeriyada waxay ku dhacdaa aminoglycosides oo ka dhan ah E. faecalis iyo enterobacteria badan, iyo mecillinam oo ka dhan ah tiro ka mid ah enterobacteria u adkaysta ampicillin.
